tailieunhanh - The correlation between emphysema’s severity on the chest computed tomography and clinical characteristics, FEV1, Chest X-RAY in patients with stable copd

Objectives: To identify the correlation between the severity of emphysema on chest CT with clinical characteristics, FEV1 and chest X-ray in stable COPD patients. Subjects: 112 COPD patients in stable stage, managed at the Respiratory Consultation Unit of Cantho Central Hospital. | Journal of military pharmaco-medicine n08-2017 THE CORRELATION BETWEEN EMPHYSEMA’S SEVERITY ON THE CHEST COMPUTED TOMOGRAPHY AND CLINICAL CHARACTERISTICS, FEV1, CHEST X-RAY IN PATIENTS WITH STABLE COPD Cao Thi My Thuy*; Dong Khac Hung**; Nguyen Van Thanh* SUMMARY Objectives: To identify the correlation between the severity of emphysema on chest CT with clinical characteristics, FEV1 and chest X-ray in stable COPD patients. Subjects: 112 COPD patients in stable stage, managed at the Respiratory Consultation Unit of Cantho Central Hospital. Study design: Descriptive cross-sectional study based on the percentage of low attenuation area less than the threshold - 950 Hounsfield Unit (%LAA ≤ 950 HU) on high resolution computed topography (HRCT) in order to identify the severity of emphysema. The clinical characteristics were selected as well as frontal and lateral chest X-ray, lung function test, classification COPD into groups A - D from GOLD 2017. Results: The severity of emphysema on chest CT is direct correlation with MRC scales (PCC = , p = ) and CAT (PCC = , p = ), but inversely correlation to the value of FEV1 after bronchodilation (PCC= , p = ). The results from emphysema evaluated on chest X-ray and %LAA ≤ 950 HU were correlated (PCC: , p: ). Conclusions: The severity of emphysema leads to cause the airway limitation in COPD. Chest X-ray has still the role for emphysema’s diagnosis. The severity of emphysema correlates with dyspnea degrees and poor health status. * Keywords: Stable chronic obstructive pulmonary disease; Emphysema; Chest CT; Clinical characteristics. INTRODUCTION Chronic obstructive pulmonary disease (COPD) is a disease characterized by incompletely reversible airway limitation. That consequence results from the increase in airway resistance due to small airway obstruction and loss of lung elastic recoil due to emphysema. The lung function testing only helps to confirm the airway limitation, but not to .