tailieunhanh - Investigation of coronary artery disease in patients with essential hypertension by dual-source 256-slide msct

Objectives: To investigate coronary artery lesions in patients with essential hypertension by Dual-source 256-slide MSCT compared to percutaneous coronary angiography. Subjects and methods: 186 patients were enrolled. All of them underwent 256-slide MSCT in Vietnam Heart Institute from 11 - 2014 to 10 - 2016. | Journal of military pharmaco-medicine no5-2017 INVESTIGATION OF CORONARY ARTERY DISEASE IN PATIENTS WITH ESSENTIAL HYPERTENSION BY DUAL-SOURCE 256-SLIDE MSCT To Thi Mai Hoa*; Pham Thi Hong Thi**; Pham Minh Thong** SUMMARY Objectives: To investigate coronary artery lesions in patients with essential hypertension by Dual-source 256-slide MSCT compared to percutaneous coronary angiography. Subjects and methods: 186 patients were enrolled. All of them underwent 256-slide MSCT in Vietnam Heart Institute from 11 - 2014 to 10 - 2016. Results: The percentage of significant coronary stenosis was . The number of 1, 2 and 3 branches with stenosis accounted for , and , respectively. Almost patients were suffered from diffuse coronary injury: LAD, RCA, LCx, LM stenosis at , , and , respectively. The proportion of patients with severe stenosis was . The percentages of LAD and RCA were higher than others. Patients with hypertension also suffered coronary calcification. Conclusion: Dual-source 256slide MSCT is not only a non-invasive approach of coronary disease, but also should be used to assess patients with essential hypertension and coronary artery disease (CAD). * Key words: Hypertension; Coronary artery disease; 256-slide computed tomography. INTRODUCTION Hypertension is one of the most common diseases and has a high mortality rate. It is also a highly prevalent risk factor for cardiovascular diseases throughout the industrialized world. According to World Health Organization (WHO), worldwide hypertension is estimated to cause million premature deaths and of the disease burden [5]. Despite of the universal acknowledgment, hypertension should be diagnosed and aggressively treated, blood pressure control rates around the world are abysmally low and shameful [5]. Coronary artery disease is one of the leading causes threating human health in developed countries and it increasingly becoming a significant public health .