tailieunhanh - Investigation of fracture rate, fractural risk factor due to osteoporosis and predicting facture risk by FRAX and GARVAN models

Objectives: To determine fracture rate, fractural risk factor, result of predicting the risk of femoral fracture by FRAX and GARVAN model. Subjects and method: We performed studying on 206 women over 40 years old including 176 in the community and 30 had fracture who lived in the Rachgia city, Kiengiang province. | Journal of military pharmaco-medicine no2-2018 INVESTIGATION OF FRACTURE RATE, FRACTURAL RISK FACTOR DUE TO OSTEOPOROSIS AND PREDICTING FACTURE RISK BY FRAX AND GARVAN MODELS Hoang Ngoc Tang*; Pham Thanh Binh*; Doan Van De* SUMMARY Objectives: To determine fracture rate, fractural risk factor, result of predicting the risk of femoral fracture by FRAX and GARVAN model. Subjects and method: We performed studying on 206 women over 40 years old including 176 in the community and 30 had fracture who lived in the Rachgia city, Kiengiang province. On each women, we performed clinical examination, found the fracture risk factors due to osteoporosis and measured bone mineral density by DEXA method on Osteocore Station Mobile machine, then we used FRAX and GARVAN model to determine level of neck femoral facture risk and other fracture risks. Result: In fracture risk factors, proportion of high age was the highest (), BMI 10 years: 165 patients (); osteoporosis: 23 patients (); 123 Journal of military pharmaco-medicine no2-2018 fall history: 38 patients (); family has member get fracture: 22 patients (). Group of risk factors with low proportion included: BMI 3% and GARVAN > 3%. Table 2: Predicting 10 years risk of femoral neck fracture by age group. Age group FRAX model GARVAN model High risk Low risk High risk Low risk 23 was , and this significant difference with p . In this research, high risk of femoral neck fracture in under weigh women was at FRAX predictive value (p < ) and at GARVAN model was 20%. According to Kanis (2008), low BMI can prognosis the risk of femoral neck fracture and this value will increase if So low BMI - one of 12 predictive factors of FRAX model - is one of the valuable factor in predicting the risk of fracture. Table 4: Predict 10 years risk of femoral neck fracture due to history fracture of family. History fracture of family FRAX model GARVAN model Low risk High risk Low risk High