tailieunhanh - Antimicrobial activity of marine fungi isolated from the Son Tra peninsula, Da Nang, VietNam

Marine fungi have become an important source of bioactive natural products. The present study was concerned with the screening of antimicrobial activity from 73 fungal strains isolated from various marine habitats collected from five different localities at the Son Tra Peninsula, Da Nang, Vietnam. | TAP CHI SINH HOC 2017, 39(4): 457-462 Antimicrobial activity of marine fungi DOI: ANTIMICROBIAL ACTIVITY OF MARINE FUNGI ISOLATED FROM THE SON TRA PENINSULA, DA NANG, VIETNAM Phan Thi Hoai Trinh1,3*, Ngo Thi Duy Ngoc1, Vo Thi Dieu Trang1, Le Quoc Phong4, Phi Quyet Tien2,3, Bui Minh Ly1,3, Tran Thi Thanh Van1,3 1 Nha Trang Institute of Technology Research and Application, VAST 2 Institute of Biotechnology, VAST 3 Graduate University of Science and Technology, VAST 4 Pasteur Institute in Nha Trang, Ministry of Health ABSTRACT: Marine fungi have become an important source of bioactive natural products. The present study was concerned with the screening of antimicrobial activity from 73 fungal strains isolated from various marine habitats collected from five different localities at the Son Tra Peninsula, Da Nang, Vietnam. For the first step of screening, ethyl acetate extract of each fungal isolate was prepared and their antimicrobial activity against the human microbial pathogens was investigated using the disc diffusion method. The panel of human microbial pathogens used were Bacillus cereus ATCC 11778, Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Listeria monocytogenes ATCC 19111, Streptococcus faecalis ATCC 19433 and Candida albicans ATCC 10231. Among 73 fungal isolates, 29 exhibited antimicrobial activity against at least two tested pathogens. The proportion of the fungal isolates having anti-microbial activity against B. cereus, S. faecalis, L. monocytogenes, S. aureus, E. coli, C. albicans and P. aeruginosa were 42, 33, 31, 22, 7, 5 and 3%, respectively. Further investigations to isolate and characterize the anti-microbial components in the extracts are needed. Keywords: Antimicrobial activity, natural products, marine fungi, microbial pathogens. Citation: Phan Thi Hoai Trinh, Ngo Thi Duy Ngoc, Vo Thi Dieu Trang, Le Quoc Phong, Phi Quyet Tien, Bui Minh Ly, Tran Thi Thanh Van, .