tailieunhanh - Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

Part 1 book “Burger’s medicinal chemistry and drug discovery” has contents: History of quantitative structure- actmty relationships, recent trends in quantitatrve structure - actmty relationships, molecular, - advances in force field approaches, and other contents. modeling in drug design, drug -target binding forces, and other contents. | MEDICINAL CHEMISTRY AND DRUG DISCOVERY Sixth Edition Volume 1: Drug Discovery Edited by Donald Department of Medicinal Chemistry School of Pharmacy - r- m Vir iversity Burger's Medicinal Chemistry and Drug Discovery is available Online in full color at . A John Wiley and Sons, Inc., Publication BURGER MEMORIAL EDITION laboratories, brought to market [Parnate, which is the brand name for tranylcypromine, a monoamine oxidase (MAO) inhibitor]. Dr. Burger was a visiting Professor at the University of Hawaii and lectured throughout the world. He founded the Journal of Medicinal Chemistry, Medicinal Chemistry Research, and published the first major reference work "Medicinal Chemistry" in two volumes in 1951. His last published work, a book, was written at age 90 (Understanding Medications: What the Label Doesn't Tell You, June 1995). Dr. Burger received the Louis Pasteur Medal of the Pasteur Institute and the Amer, ican Chemical Society Smissman Award. Dr. Burger played the violin and loved classical music. He was married for 65 years to Frances Page Burger, a genteel Virginia lady who always had a smile and an open house for the Professor's graduate students and postdoctoral fellows. The Sixth Edition of Burger's Medicinal Chemistry and Drug Discovery is being designated as a Memorial Edition. Professor Alfred Burger was born in Vienna, Austria on September 6, 1905 and died on December 30, 2000. Dr. Burger received his . from the University of Vienna in 1928 and joined the Drug Addiction Laboratory in the Department of Chemistry at the University of Virginia in 1929. During his early years at UVA, he synthesized fragments of the morphine molecule in an attempt to find the analgesic pharmacophore. He joined the UVA chemistry faculty in 1938 and served the department until his retirement in 1970. The chemistry department at UVA became the major academic training ground for medicinal chemists because of Professor

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