tailieunhanh - Distribution and exposure assessment through inhalation and dermal pathways to phthalates in indoor air collected from Hanoi, Vietnam
Phthalates (phthalic diesters) is one of endocrine disrupting compound groups which have been recently concerned of the occurrence and harmful effects to human health. In this report, ten common phthalates were analyzed in indoor air collected from hair salons and homes collected from Hanoi, Vietnam. Total concentrations of phthalates in indoor air ranged from 306 to 16000 ng/m3 (mean: 1140 ng/m3 ). High concentrations of phthalates were measured in indoor air collected from hair salons (mean: 4040 ng/m3 ). Among the studied phthalates, diethyl phthalate (DEP) was predominant compound and had the highest levels in indoor air. | Vietnam Journal of Science and Technology 55 (4C) (2017) 319-325 DISTRIBUTION AND EXPOSURE ASSESSMENT THROUGH INHALATION AND DERMAL PATHWAYS TO PHTHALATES IN INDOOR AIR COLLECTED FROM HANOI, VIETNAM Le Thi Hanh1, Le Minh Thuy1, Le Van Chieu2, Dang Minh Huong Giang1, Tran Manh Tri1, Tu Binh Minh1, * 1 Faculty of Chemistry, VNU University of Science, 19 Le Thanh Tong Street, Hanoi, Vietnam 2 Vietnam National University, Hanoi, 144 Xuan Thuy, Cau Giay, Hanoi, Vietnam * Email: tubinhminh@ Received: 11 July 2017; Accepted for publication: 20 October 2017 ABSTRACT Phthalates (phthalic diesters) is one of endocrine disrupting compound groups which have been recently concerned of the occurrence and harmful effects to human health. In this report, ten common phthalates were analyzed in indoor air collected from hair salons and homes collected from Hanoi, Vietnam. Total concentrations of phthalates in indoor air ranged from 306 to 16000 ng/m3 (mean: 1140 ng/m3). High concentrations of phthalates were measured in indoor air collected from hair salons (mean: 4040 ng/m3). Among the studied phthalates, diethyl phthalate (DEP) was predominant compound and had the highest levels in indoor air. Based on the measured concentrations, the human exposure to phthalates through inhalation and dermal absorption were estimated for various age groups. Overall, the exposure doses decreased with increasing ages. Keywords: phthalates, indoor air, human exposure, inhalation, dermal. 1. INTRODUCTION Phthalate di-esters were firstly introduced in 1920s [1]. They are industrial synthetic chemicals that have been widely used to improve the flexibility of plastic materials. So, their occurrence is everywhere in our lives, from personal care products, food wrap films, children’s toys or even in medical equipment. Moreover, diisobutyl phthalate (DiBP) was also used as a light-resistant plasticizer for paints. Globally, over 470 million pounds of phthalates are produced every year. In .
đang nạp các trang xem trước
