tailieunhanh - Testosterone and gonadotropins in male adults with cryptorchidism: Compare pre-and post orchidopexy

Objectives: To compare testosterone and gonadotropins characteristics of cryptorchidism in male adults before and after orchidopexy. Subjects and methods: In a follow-up study on 112 adult patients, who were operatived by orchidopexy. | Journal of military pharmaco-medicine no4-2018 TESTOSTERONE AND GONADOTROPINS IN MALE ADULTS WITH CRYPTORCHIDISM: COMPARE PRE- AND POST-ORCHIDOPEXY Nguyen Manh Thang*; Tran Quan Anh**; Nguyen Quang** SUMMARY Objectives: To compare testosterone and gonadotropins characteristics of cryptorchidism in male adults before and after orchidopexy. Subjects and methods: In a follow-up study on 112 adult patients, who were operatived by orchidopexy. Analyzing characteristics of their hormones including LH, FSH, testosterone, compared pre- and post-operation. Results: Mean age was ± (15 - 43 years old). Average LH/FSH/testosterone. Pre-orchidopexy: unilateral ± ± ± . Bilateral: ± ± ± . Post orchidopexy: average LH/FSH/testosterone were different between two groups: unilateral ± ± ± . Bilateral ± ± ± . Average LH, FSH decreased. Average testosterone increased. Conclusions: There is an improvement in testosterone and gonadotropin in male adults with cryptorchidism post-operation, althought there is difference between two groups: bilateral and unilateral. * Keywords: Adult cryptorchidism; Testosterone; Gonadotropins; Orchidopexy. INTRODUCTION Cryptorchidism is one of the most common congenital condition in the pediatric population. This is a disorder in which one or both of the testes do not descend spontaneously to the usual position in the scrotum. About 3% of fullterm and 30% of premature infant boys are born with at least one undescended testis [2, 6, 10]. Cryptorchidism is more commonly seen in premature males because the testes do not descend from the abdomen to the scrotal sac until the seventh month of fetal development [2, 8]. Cryptorchidism is associated with impairment of germ cell maturation and subsequent infertility in adulthood. It's common knowledge that the increased temperature in undescended testis affects spermatogeneis rather than hormonal levels .