tailieunhanh - Ebook Textbook of biochemistry: Part 2

(BQ) Part 2 book "Textbook of biochemistry" presents the following contents: Electrolyte and water balance, metabolic diseases, free radicals and antioxidants, mineral metabolism and abnormalities, energy metabolism and nutrition, nucleotides chemistry and metabolism,. Invite you to consult. | CHAPTER 30 Electrolyte and Water Balance Chapter at a Glance The reader will be able to answer questions on the following topics Intake and output of water Osmolality of extracellular fluid Electrolyte composition of body fluids Regulation of sodium and water balance Renin-angiotensin system Isotonic hypotonic hypertonic contraction ECF Isotonic hypotonic hypertonic expansion ECF Sodium metabolism Potassium metabolism Chloride metabolism The maintenance of extracellular fluid volume and pH are closely interrelated. The body water compartments are shown in Box . Body is composed of about 60-70 water. Distribution of water in different body water compartments depends on the solute content of each compartment. Osmolality of the intra- and extracellular fluid is the same but there is marked difference in the solute content. Box The body water compartments Total body waMr IỂ0 of ÌMƠy WBiohtJ Intracellular 2B Lt Exlm-tilulur 14 L iflHb Cil tiiKly M ci body l. iL auLiiLular Extra cu tar 11 ÍLí I INTAKE AND OUTPUT OF WATER During oxidation of foodstuffs 1 g carbohydrate produces mL of water 1 g protein releases mL water and 1 g fat generates mL of water. Intake of 1000 kcal produces 125 mL water Table . The major factors controlling the intake are thirst and the rate of metabolism. The thirst center is stimulated by an increase in the osmolality of blood leading to increased intake. The renal function is the major factor controlling the rate of output. The rate of loss through skin is influenced by TABLE Water balance in the body Intake per day Output per day Water in food 1250mL Urine 1500mL Oxidation of food 300 mL Skin 500 mL Drinking water 1200mL Lungs 700 mL Feces 50 mL 2750 mL 2750 mL 408 Textbook of Biochemistry the weather the loss being more in hot climate perspiration and less in cold climate. Loss of water through skin is increased to 13 for each degree centigrade rise in body temperature during fever. I OSMOLALITY OF .

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