tailieunhanh - Chaper 30: Breast cancer

Cancer of the breast is the most common cancer in women worldwide. Every year million women are newly diagnosed with breast cancer glo-cancer accounts for 23% of all female cancers glo-bally and shows a geographic variation in incidenc are 39 per 100,000 worldwide – 27 in less and 66 usually applied in single-center institutions per 100,000 in the more developed regions. Out of the 425,000 global annual deaths from breast cancer, however, 68,000 are young women from develop-duce major improvements wit limited financialing countries1. | 30 Breast Cancer Regine Unkels and Eva J. Kantelhardt INTRODUCTION Cancer in developing countries was not considered a priority until recently. Since non-communicable diseases were the major topic at the general assembly of the United Nations UN in September 2011 this opinion has definitely changed within the international community. The four main noncommunicable diseases - cardiovascular disease chronic lung diseases diabetes and cancer - kill three in five people worldwide causing great socioeconomic harm particularly in developing nations. Cancer of the breast is the most common cancer in women worldwide. Every year million women are newly diagnosed with breast cancer globally and around 425 000 die of the disease. Breast cancer accounts for 23 of all female cancers globally and shows a geographic variation in incidence and death rates. Age-standardized incidence rates are 39 per 100 000 worldwide - 27 in less and 66 per 100 000 in the more developed regions. Out of the 425 000 global annual deaths from breast cancer however 68 000 are young women from developing countries1. Survival is highly dependent on resources available - there is a strong association between gross domestic product and survival2. As you can see breast cancer is a public health problem it attacks women in their most productive years of life. Breast cancer can be cured with limited resources if detected early but treating advanced-stage disease is expensive and outcome is often poor. Early detection can improve survival and thus can save costs and lives. It is obvious that an early detection program for low-resource settings is needed but implementation and planning need financial and human resource allocation which might be difficult to assure. International organizations such as the Breast Health Global Initiative BHGI together with the World Health Organization WHO are working on evidence-based guidelines for early detection diagnosis and treatment of breast cancer in different .

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