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Báo cáo khoa học: " Detecting early kidney damage in horses with colic by measuring matrix metalloproteinase -9 and -2, other enzymes, urinary glucose and total proteins"

Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú y đề tài: Detecting early kidney damage in horses with colic by measuring matrix metalloproteinase -9 and -2, other enzymes, urinary glucose and total proteins. | Acta Veterinaria Scandinavica BioMed Central Research Open Access Detecting early kidney damage in horses with colic by measuring matrix metalloproteinase -9 and -2 other enzymes urinary glucose and total proteins Bela M Arosalo Marja Raekallio Minna Rajamaki Elina Holopainen Tuulia Kastevaara Hanna Salonen and Satu Sankari Address Department of Equine and Small Animal Medicine Pharmacology and Toxicology Faculty of Veterinary Medicine P.O. Box 57 00014 University of Helsinki Finland Email Bela M Arosalo - bela.arosalo@hevossairaala.fi Marja Raekallio - marja.raekallio@helsinki.fi Minna Rajamaki - Minna.m.rajamaki@helsinki.fi Elina Holopainen - elina.kummola@somero.fi Tuulia Kastevaara - tuulia.kastevaara@dnaintervet.net Hanna Salonen - hanna.salonen@fimnet.fi Satu Sankari - satu.sankari@helsinki.fi Corresponding author Published 23 January 2007 Received 30 March 2006 Accepted 23 January 2007 Acta Veterinaria Scandinavica 2007 49 4 doi 10.1186 1751-0147-49-4 This article is available from http www.actavetscand.cOm content 49 1 4 2007 Arosalo et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The aim of the study was to investigate urine matrix metalloproteinase MMP-2 and -9 activity alkaline phosphatase creatinine U-AP Cr and gamma-glutamyl-transpeptidase creatinine U-GGT Cr ratios glucose concentration and urine protein creatinine U-Prot Cr ratio and to compare data with plasma MMP-2 and -9 activity cystatin-C and creatinine concentrations in colic horses and healthy controls. Horses with surgical colic n 5 were compared to healthy stallions n 7 that came for castration. Blood and urine samples were collected. MMP gelatinolytic activity was measured by zymography. Results We found out that horses .