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báo cáo khoa học: "Vulval elephantiasis as a result of tubercular lymphadenitis: two case reports and a review of the literature"
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Vulval elephantiasis as a result of tubercular lymphadenitis: two case reports and a review of the literature | Chintamani et al. Journal of Medical Case Reports 2010 4 369 http www.jmedicalcasereports.eom content 4 1 369 jAl JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Vulval elephantiasis as a result of tubercular lymphadenitis two case reports and a review of the literature 1 1 1 1 1 1 Chintamani JP Singh Megha Tandon Rohan Khandelwal Tushar Aeron Sidharth Jain 1 1 1 r- r- 1 2 Nikhil Narayan Rahul Bamal Yashwant Kumar S Srinivas Sunita Saxena Abstract Introduction Elephantiasis as a result of chronic lymphedema is characterized by gross enlargement of the arms legs or genitalia and occurs due to a variety of obstructive diseases of the lymphatic system. Genital elephantiasis usually follows common filariasis and lymphogranuloma venereum. It may follow granuloma inguinale carcinomas lymph node dissection or irradiation and tuberculosis but this happens rarely. Vulval elephantiasis as a consequence of extensive lymph node destruction by tuberculosis is very rare. We present two very unusual cases of vulval elephantiasis due to tuberculous destruction of the inguinal lymph nodes. Case presentation Two Indian women - one aged 40 years and the other aged 27 years with progressively increasing vulval swellings over a period of five and four years respectively - presented to our hospital. In both cases there was a significant history on presentation. Both women had previously taken a complete course of anti-tubercular treatment for generalized lymphadenopathy. The vulval swellings were extremely large in the first case report measuring 35 X 25 cm on the right side and 45 X 30 cm on the left side weighing 20 lb and 16 lb respectively. Both cases were managed by surgical excision with reconstruction and the outcome was positive. Satisfactory results have been maintained during a follow-up period of six years in both cases. Conclusions Elephantiasis of the female genitalia is unusual and it has rarely been reported following tuberculosis. We report two cases of vulval