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báo cáo hóa học:" Psychometric properties of two measures of psychological well-being in adult growth hormone deficiency"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Psychometric properties of two measures of psychological well-being in adult growth hormone deficiency | BioMed Central Health and Quality of Life Outcomes Research Open Access Psychometric properties of two measures of psychological well-being in adult growth hormone deficiency Carolyn V McMillan1 Clare Bradley 1 James Gibney2 David L Russell-Jones3 and Peter H Sonksen4 Address Department of Psychology Royal Holloway University of London Egham Surrey TW20 0EX UK 2Department of Endocrinology Adelaide Meath Hospitals incorporating the National Children s Hospital Tallaght Dublin 24 Eire UK 3Department of Diabetes and Endocrinology Royal Surrey County Hospital Guildford UK and 4GKT School of Medicine St Thomas Campus London UK Email Carolyn V McMillan - c.mcmillan@rhul.ac.uk Clare Bradley - c.bradley@rhul.ac.uk James Gibney- james.gibney@amnch.ie David L Russell-Jones - drj@royalsurrey.nhs.uk Peter H Sonksen - peter.sonksen@kcl.ac.uk Corresponding author Published 22 March 2006 Received 15 December 2005 Accepted 22 March 2006 Health and Quality of Life Outcomes 2006 4 16 doi l0.ll86 l477-7525-4-l6 r This article is available from http www.hqlo.cOm content 4 l l6 2006 McMillan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Psychometric properties of two measures of psychological well-being were evaluated for adults with growth hormone deficiency GHD the General Well-being Index GWBI - British version of the Psychological General Well-being Index and the l2-item Well-being Questionnaire W-BQl2 . Methods Reliability structure and other aspects of validity were investigated in a cross-sectional study of l57 adults with treated or untreated GHD and sensitivity to change in a randomised placebo-controlled study of three months growth hormone GH withdrawal from l2 of 2l GH-treated adults. Results Very high .