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Báo cáo y học: " Large cell non-Hodgkin’s lymphoma masquerading as renal carcinoma with inferior vena cava thrombosis: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Large cell non-Hodgkin’s lymphoma masquerading as renal carcinoma with inferior vena cava thrombosis: a case report. | Samlowski et al. Journal of Medical Case Reports 2011 5 245 http www.jmedicalcasereports.eom content 5 1 245 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Large cell non-Hodgkin s lymphoma masquerading as renal carcinoma with inferior vena cava thrombosis a case report Erika E Samlowski 1 Christopher Dechet2 Alan Weissman1 and Wolfram E Samlowski1 3 Abstract Introduction Many cancers are associated with inferior vena cava IVC obstruction but very few cancers have the ability to propagate within the lumen of the renal vein or the IVC. Renal cell carcinoma is the most common of these cancers. Renal cancer with IVC extension has a high rate of recurrence and a low five year survival rate. Case presentation A 62-year-old Caucasian woman previously in good health developed the sudden onset of severe reflux symptoms and right-sided abdominal pain that radiated around the right flank. A subsequent ultrasound and CT scan revealed a right upper pole renal mass with invasion of the right adrenal gland liver left renal vein and IVC. This appeared to be consistent with stage III renal cancer with IVC extension. Metastatic nodules were believed to be present in the right pericardial region the superficial anterior abdominal wall the left perirenal abdominal and pelvic regions and the left adrenal gland. The pattern of these metastases as well as the invasion of the liver by the tumor was thought to be atypical of renal cancer. A needle biopsy of a superficial abdominal wall mass revealed a surprising finding The malignant cells were diagnostic of large-cell B-cell nonHodgkin s lymphoma. The lymphoma responded dramatically to systemic chemotherapy which avoided the need for nephrectomy. Conclusion Lymphomas only rarely progress via intraluminal vascular extension. We have been able to identify only one other case report of renal lymphoma with renal vein and IVC extension. While renal cancer would have been treated with radical nephrectomy and tumor embolectomy .