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Role of diffusion-weighted imaging in the diagnosis of gynecological diseases

Providers who agreed to participate and scheduled an interview were sent a consent form for the study and a baseline questionnaire (on services provided, type of clinical staff employed, and number of WHP clients served) by email or fax to be returned to the interviewers. The phone interviews lasted approximately 20-30 minutes each, were conducted by 2 researchers in order for one to take notes, and were based upon interview guides developed for PPFA providers and non-PPFA providers. Recognizing that responses on this topic could be sensitive, respondents were guaranteed that their identities would remain confidential and the non-Planned. | Eur Radiol 2009 19 745-760 DOI 10.1007 S00330-008-1185-5 UROGENITAL Tomohiro Namimoto Kazuo Awai Takeshi Nakaura Yumi Yanaga Toshinori Hirai Yasuyuki Yamashita Role of diffusion-weighted imaging in the diagnosis of gynecological diseases Received 11 June 2008 Revised 6 August 2008 Accepted 30 August 2008 Published online 7 October 2008 European Society of Radiology 2008 T. Namimoto S K. Awai . T. Nakaura . Y. Yanaga . T. Hirai . Y. Yamashita Department of Diagnostic Radiology Graduate School of Medical Sciences Kumamoto University 1-1-1 Honjo Kumamoto 860-8556 Japan e-mail namimottoo@yahoo.co.jp Tel. 81-96-3735261 Fax 81-96-3624330 Abstract Recent technical advances in diffusion-weighted imaging DWI greatly enhanced the clinical value of magnetic resonance imaging MRI of the body. DWI can provide excellent tissue contrast based on molecular diffusion and may be able to demonstrate malignant tumors. Quantitative measurement of the apparent diffusion coefficient ADC may be valuable in distinguishing between malignant and benign lesions. We reviewed DWI and conventional MRI of the female pelvis to study the utility of DWI in patients with gynecological diseases. Although the ADC can help to differentiate between normal and cancerous tissue in the uterine cervix and endometrium its utility may be limited by the large overlap of the uterine myometrium and ovaries. On the other hand the ADC may be useful for monitoring the therapeutic outcome after uterine arterial embolizati UAE chemotherapy and or radiation therapy. In patients with ovarian cancer DWI demonstrates high intensity not only at the primary cancer site but also in disseminated peritoneal implants. When added to conventional MRI findings DWI and ADC values provide additional information and DWI may play an important role in the diagnosis of patients with gynecological diseases. Keywords Diffusion . ADC . Magnetic resonance imaging . Uterus . Ovary Introduction Although diffusion-weighted imaging DWI now .