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báo cáo hóa học: " A prospective study of decline in lung function in relation to welding emissions"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài:A prospective study of decline in lung function in relation to welding emissions | Journal of Occupational Medicine and Toxicology BioMed Central Research A prospective study of decline in lung function in relation to welding emissions Sigve W Christensen1 Jens Peter Bonde 2 and 0yvind Omland1 3 Address Department of Occupational Medicine Aalborg Hospital Arhus University Hospital Aalborg Denmark 2Department of Occupational Medicine Arhus Hospital Arhus University Hospital Arhus Denmark and institute of Public Health Dept. of Occupational and Environmental Medicine University of Arhus Arhus Denmark Email Sigve W Christensen - Sigve.W.Christensen@sygehusviborg.dk Jens Peter Bonde - jpbon@as.aaa.dk 0yvind Omland - oo@rn.dk Corresponding author Open Access Published 26 February 2008 Received 14 August 2007 J-I-. z J_- 1 I mz i-rzr zz-r- z Accepted 26 February 2008 Journal of Occupational Medicine and Toxicology 2008 3 6 doi l0.ll 86 1745-6673-3-6 This article is available from http www.occup-med.cOm content 3 1 6 2008 Christensen et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Numerous cross-sectional studies have reported reduced lung function among welders but limitations of exposure assessment and design preclude causal inference. The aim of this study was to investigate if long-term exposure to welding fume particulates accelerates the age-related decline in lung function. Methods Lung function was measured by spirometry in 1987 and 2004 among 68 steel welders and 32 non-welding production workers. The decline in forced expiratory volume FEV1 was analysed in relation to cumulated exposure to fume particulates among welders during the followup period. Results Among smokers the decline in FEVl through follow-up period was in average l50 ml larger among welders than non-welders .