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Antioxidant capacity in relationship to serum lipid peroxides levels in healthy elderly of Mexico City*

In our second gambling experiment subjects were asked to make six choices. For each choice subjects had to select one of two decks of 10 cards. Unlike Bechara et al. experiment, subjects saw the payoffs from each of the ten cards in the pair of decks before making their selection. Once they decided which deck they wanted, the ten cards were shuffled and the subjects selected one card. In all six choices one of the two decks had a positive mean payoff, and the other deck had a nonpositive payoff. The deck with the positive average payoff had a. | Bioquímica Clínica Antioxidant capacity in relationship to serum lipid peroxides levels in healthy elderly of Mexico City Martha A. Sánchez-Rodríguez1 Raquel Retana-Ugalde1 Mirna Ruiz-Ramos1 Victor Manuel Mendoza-Nunez2 1. MD. 2. ScD. Unidad de Investigación en Gerontologia Facultad de Estudios Superiores Zaragoza Universidad Nacional Autónoma de Mexico UNAM . Batalla 5 de Mayo s n esq. Fuerte de Loreto Col. EJercito de Oriente C.P. 09230 Mexico City Mexico. Acta Bioquímica Clínica Latinoamericana Incorporada al Chemical Abstract Service. Código bibliografico ABCLDL. ISSN 0325-2957 Summary The aging is one of the factors that cause decrease in the antioxidant capacity. Likewise it has been proposed that subjects exposed permanently to air pollution develop deficient antioxidant capacity to oxidative stress OxS . This study aimed to analyze the antioxidant capacity against elevated lipid peroxides in healthy elderly of Mexico City. 105 adults 44 10.8 years and 126 elderly subjects were studied 68 7.1 years residents of Mexico City clinically healthy non-smokers non-vitamin supplement takers who had lived in the city for 10 years. Plasma lipoperoxides LPO total antioxidant status TAS the activity of red blood cells superoxide dismutase SOD and plasma glutathione peroxidase GPx were studied in all subjects. LPO levels were found significantly higher p 0.05 in the elderly subjects in comparison with the adults in addition TAS and GPx were higher in adults than among the elderly people p 0.0001 . Nevertheless SOD was similar in both groups p 0.346 . These findings reveal that the elderly residents of Mexico City have TAS and GPx lower than adults and similar SD activity probably due to the fact that these antioxidants are neutralizing the higher LPO levels of elderly people. Therefore this mechanism could be considered as an efficient antioxidant capacity in the elderly as response to high LPO levels since the health status mortality prevalence and life span life of the