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Báo cáo y học: "Assessing the effect of HAART on change in quality of life among HIV-infected women."

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Assessing the effect of HAART on change in quality of life among HIV-infected women. | BioMed Central AIDS Research and Therapy Research Open Access Assessing the effect of HAART on change in quality of life among HIV-infected women Chenglong Liu1 2 Kathleen Weber3 Esther Robison4 Zheng Hu1 Lisa P Jacobson1 and Stephen J Gange 1 Address Department of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA 2Department of Medicine Georgetown University School of Medicine Washington DC USA 3The CORE Center at John H. Stroger Jr Hospital of Cook County Chicago IL USA and 4Montefiore Medical Center New York NY USA Email Chenglong Liu - cl278@georgetown.edu Kathleen Weber - weberkathleen@ameritech.net Esther Robison - ERobi220@aol.com Zheng Hu - zhu@jhsph.edu Lisa P Jacobson - ljacobso@jhsph.edu Stephen J Gange - sgange@jhsph.edu Corresponding author Published 20 March 2006 Received 13 January 2006 Accepted 20 March 2006 AIDS Research and Therapy2006 3 6 doi l0.ll86 l 742-6405-3-6 This article is available from http www.aidsrestherapy.cOm content 3 1 6 2006Liu et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The impact of highly active antiretroviral therapy HAART on health-related quality of life QOL of HIV-1 infected individuals in large prospective cohorts has not been well studied. Objective To assess the effect of HAART on QOL by comparing HIV-infected women using HAART with HIV-infected women remaining HAART naive in the Women s Interagency HIV Study WIHS a multicenter prospective cohort study begun in 1994 in the US. Methods A l l matching with equivalent 0. l propensity scores for predicting HAART initiation was implemented and 458 pairs were obtained. HAART effects were assessed using pattern mixture models. The changes of nine QOL domain scores and one .