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Báo cáo khoa học: Induction of actin cytoskeleton rearrangement by methyl okadaate – comparison with okadaic acid

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Methyl okadaate is a derivative of the lipophilic polyether okadaic acid (OA), a well-known inducer of apoptosis. OA inhibits Ser⁄Thr protein phosphatases (PPs), among them types 1 and 2A (PP1 and PP2A), whereas methyl okadaate lacks PP1⁄PP2A inhibitory activityin vitro.

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