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Báo cáo khoa học: Purification and functional characterization of human 11b hydroxylase expressed in Escherichia coli
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The human 11b-hydroxylase (hCYP11B1) is responsible for the conversion of 11-deoxycortisol into the major mammalian glucocorticoid, cortisol. The reduction equivalents needed for this reaction are provided via a short elec-tron transfer chain consisting of a [2Fe-2S] ferredoxin and a FAD-contain-ing reductase.