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Canadian Centre for Occupational Health and Safety

Several effects have already been shown in animals. Among these, toxic effects have been identified in several organs (heart, lungs, kidneys, reproductive system ), as well as genotoxicity and cytotoxicity. For example, some particles cause granulomas, fibrosis and tumoural reactions in the lungs. Thus, titanium dioxide, a substance recognized as having low toxicity, shows high pulmonary toxicity on the nano-scale in some studies and no or almost no effects in other studies. In general, the toxicological data specific to nanoparticles remains limited, often rendering quantitative risk assessment difficult due to the small number of studies for most substances, the short exposure. | Canadian Centre for Occupational Health and Safety 2008-2009 Estimates Report on Plans and Priorities Approved Minister of Labour and Minister of the Economic Development Agency of Canada for the Regions of Quebec Table of Contents Section I Overview A. Minister s Message .3 B. Management Representation Statement.4 C. Raison d etre.5 D. Organization Information.5 E. Program Activity Architecture.6 F. Voted and Statutory Items listed in Main Estimates.7 G. Departmental Planned Spending and Full Time Equivalent.7 H. Summary Information.8 Section II Analysis of Program Activities by Strategic Outcome A. Operating Environment.11 2.1 Key Stakeholders and Partners .11 2.2 Major initiatives.12 2.3 Risks and Challenges.13 2.4 Link to the Government of Canada Outcomes .14 B. Total Planned Spending by Strategic Outcome .15 2.5 Easy Access to Occupational Health and Safety Information and Service.17 2.6 Application of Occupational Health and Safety Information to Improve Workplace Practices.18 2.7 Increased Awareness and Understanding.20 2.8 Partial Recovery of Costs from User Fees.21 Section III Supplementary Information Table 1 Departmental Links to Government of Canada Outcomes.22 Table 2 Services Received Without Charge.23 Table 3 Source of Respendable Revenue.23 Section IV Other Items of Interest Annex 1 Listing of Statutes and Regulations.24 Annex 2 Publications.24 Annex 3 Government-wide and Horizontal Initiatives.24 Annex 4 Strategic Priorities.25 Section I Overview A. Minister s Message As Canada s national occupational health and safety resource the Canadian Centre for Occupational Health and Safety CCOHS is uniquely equipped to provide leadership to help foster the much needed shift to a more fully integrated health and safety culture. As Minister of Labour and Minister of the Economic Development Agency of Canada for the Regions of Quebec I am proud to present the Centre s Report on Plans and Priorities for 20082009. CCOHS is Canada s national occupational health