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Báo cáo sinh học: " The Israeli strain IS-98-ST1 of West Nile virus as viral model for West Nile encephalitis in the Old World"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: The Israeli strain IS-98-ST1 of West Nile virus as viral model for West Nile encephalitis in the Old World | Virology Journal BioMed Central Short report Open Access The Israeli strain IS-98-STI of West Nile virus as viral model for West Nile encephalitis in the Old World Marianne Lucas1 Marie-Pascale Frenkiel1 Tomoji Mashimo2 3 JeanLouis Guénet2 Vincent Deubel4 5 Philippe Desprès1 and Pierre-Emmanuel Ceccaldi 6 7 Address 1Unité des Interactions Moléculaires Flavivirus-Hôtes Institut Pasteur Paris France 2Unité de Génétique des Mammiíères Institut Pasteur Paris France institute of Laboratory Animals Kyoto University Graduate School of Medicine Kyoto Japan 4Unité de Biologie des Infections Virales Emergentes Institut Pasteur Lyon France 5Institut Pasteur of Shangai Shangai P.R. China 6Département de Virologie Institut Pasteur Paris France and 7Unité Epidémiologie et Physiopathologie des Virus Oncogènes Institut Pasteur Paris France Email Marianne Lucas - mlucas@pasteur.fr Marie-Pascale Frenkiel - mpfrenk@pasteur.fr Tomoji Mashimo - tmashimo@anim.med.kyoto-u.ac.jp Jean-Louis Guénet - guenet@pasteur.fr Vincent Deubel - vdeubel@cervi-lyon.inserm.fr Philippe Desprès - pdespres@pasteur.fr Pierre-Emmanuel Ceccaldi - ceccaldi@pasteur.fr Corresponding author Published 18 November 2004 Received 08 October 2004 Accepted 18 November 2004 Virology Journal 2004 1 9 doi l0.ll86 l743-422X-l-9 This article is available from http www.virologyj.com content l l 9 2004 Lucas et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract West Nile virus WNV recently became a major public health concern in North America the Middle East and Europe. In contrast with the investigations of the North-American isolates the neurovirulence properties of Middle-Eastern strains of WNV have not been extensively characterized. Israeli WNV strain IS-98-STl that has