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Báo cáo y học: "The effect of voluntary fasting and dehydration on flicker-induced retinal vascular dilation in a healthy individual: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: The effect of voluntary fasting and dehydration on flicker-induced retinal vascular dilation in a healthy individual: a case report | Journal of Medical Case Reports BioMed Central Case report Open Access The effect of voluntary fasting and dehydration on flicker-induced retinal vascular dilation in a healthy individual a case report Rebekka Heitmar Doina Gherghel Richard Armstrong Robert Cubbidge and Sarah Hosking Address School of Life and Health Sciences Aston University Birmingham UK Email Rebekka Heitmar - heitmarr@aston.ac.uk Doina Gherghel - D.Gherghel@aston.ac.uk Richard Armstrong - r.a.armstrong@aston.ac.uk Robert Cubbidge - r.p.cubbidge@aston.ac.uk Sarah Hosking - s.l.hosking@aston.ac.uk Corresponding author Published 13 May 2008 Received 23 August 2007 Journal of Medical Case Reports 2008 2 153 doi 10.1186 1752-1947-2-153 Accepted 1 3 May 2008 This article is available from http www.jmedicalcasereports.cOm content 2 1 153 2008 Heitmar et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Dynamic retinal vessel analysis represents a well-established method for the assessment of vascular reactivity during both normal conditions and after various provocations. We present a case where the subject showed abnormal retinal vessel reactivity after fasting voluntarily for 20 hours. Case presentation A healthy 21-year-old man who fasted voluntarily for 20 hours exhibited abnormal retinal vascular reactivity dilation and constriction after flicker provocation as measured using the Dynamic Retinal Vessel Analyser Imedos Jena Germany . Conclusion The abnormal vascular reactivity induced by fasting was significant abnormal levels of important nutrients due to fasting and dehydration could play a role through altering the concentration of vasoactive substances such as nitric oxide. This hypothesis needs further investigation. .