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Báo cáo y học: "Anemia and red blood cell transfusion in neurocritical care"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Anemia and red blood cell transfusion in neurocritical care. | Available online http ccforum.eom content 13 3 R89 Research Anemia and red blood cell transfusion in neurocritical care Andreas H Kramer1 and David A Zygun2 Departments of Critical Care Medicine Clinical Neurosciences University of Calgary Foothills Medical Center 1403 29thSt. N.W. Calgary AB Canada T2N 2T9 departments of Critical Care Medicine Clinical Neurosciences Community Health Sciences University of Calgary Foothills Medical Center 1403 29thst. N.W. Calgary AB Canada T2N 2T9 Corresponding author Andreas H Kramer andreas.kramer@albertahealthservices.ca Received 26 Jan 2009 Revisions requested 3 Mar 2009 Revisions received 9 Apr 2009 Accepted 11 Jun 2009 Published 11 Jun 2009 Critical Care 2009 13 R89 doi 10.1186 cc7916 This article is online at http ccforum.com content 13 3 R89 2009 Kramer and Zygun licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Anemia is one of the most common medical complications to be encountered in critically ill patients. Based on the results of clinical trials transfusion practices across the world have generally become more restrictive. However because reduced oxygen delivery contributes to secondary cerebral injury anemia may not be as well tolerated among neurocritical care patients. Methods The first portion of this paper is a narrative review of the physiologic implications of anemia hemodilution and transfusion in the setting of brain-injury and stroke. The second portion is a systematic review to identify studies assessing the association between anemia or the use of red blood cell transfusions and relevant clinical outcomes in various neurocritical care populations. Results There have been no randomized controlled trials that have adequately assessed .