Đang chuẩn bị liên kết để tải về tài liệu:
Allosteric inhibition of CRISPR-Cas9 by bacteriophage-derived peptides

Đang chuẩn bị nút TẢI XUỐNG, xin hãy chờ

CRISPR-Cas9 has been developed as a therapeutic agent for various infectious and genetic diseases. In many clinically relevant applications, constitutively active CRISPR-Cas9 is delivered into human cells without a temporal control system. Excessive and prolonged expression of CRISPR-Cas9 can lead to elevated off-target cleavage. |

TÀI LIỆU LIÊN QUAN

Allosteric inhibition of CRISPR-Cas9 by bacteriophage-derived peptides

Overcoming Bcr-Abl T315I mutation by combination of GNF-2 and ATP competitors in an Abl-independent mechanism

The 4-(dimethylaminoalkyl)piperazine inhibitors of α-glucosidase: allosteric enzyme inhibition and identification of interacting chemical groups