Đang chuẩn bị liên kết để tải về tài liệu:
Identifying specific matrix metalloproteinase-2-inhibiting peptides through phage display-based subtractive screening

Đang chuẩn bị nút TẢI XUỐNG, xin hãy chờ

Gelatinases A and B, which are members of the matrix metalloproteinase (MMP) family, play essential roles in cancer development and metastasis, as they can break down basal membranes. Therefore, the determination and inhibition of gelatinases is essential for cancer treatment. Peptides that can specifically block each gelatinase may, therefore, be useful for cancer treatment. In this study, subtractive panning was carried out using a 12-mer peptide library to identify peptides that block gelatinase A activity (MMP-2), which is a key pharmacological target. Using this method, 17 unique peptide sequences were determined. |

TÀI LIỆU LIÊN QUAN

Identifying the family line culture of Vietnamese people

A novel path-specific effect statistic for identifying the differential specific paths in systems epidemiology

Báo cáo y học: "MONKEY: identifying conserved transcription-factor binding sites in multiple alignments using a binding site-specific evolutionary model"

MFSPSSMpred: Identifying short disorder-to-order binding regions in disordered proteins based on contextual local evolutionary conservation

Identifying specific matrix metalloproteinase-2-inhibiting peptides through phage display-based subtractive screening

3DeFDR: Statistical methods for identifying cell type-specific looping interactions in 5C and Hi-C data

Identifying specific non-attending groups in breast cancer screening - population-based registry study of participation and socio-demography

Identifying gene-specific subgroups: An alternative to biclustering

Identifying branch-specific positive selection throughout the regulatory genome using an appropriate proxy neutral

Identifying specific needs in adult cystic fbrosis patients: A pilot study using a custom questionnaire