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Listeria monocytogenes strain BN3 responds to acyl homoserine lactone (AHL) by expression of virulence gene (HLYA) and gene responsible for biofilm (SRTA)

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In response to 500 nM AHL, (C4-HSL treated) strain BN3 showed 27-fold up-regulation of srtA gene (encodes enzyme sortase) as compared to control. Our study confirmed the cross-talk between Gram-positive and Gram-negative bacteria since L. monocytogenes strain BN3 responds to C4-HSL, which is normally produced by Gram-negative bacteria. |