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Combination chemoradiotherapy with temozolomide, vincristine, and interferon-β might improve outcomes regardless of O6- methyl-guanine-DNA-methyltransferase (MGMT) promoter methylation status in newly glioblastoma

This investigator-initiated, open-label, single-arm, single-institute study was conducted to investigate the effectiveness of induction combination chemoradiotherapy and long-term maintenance therapy with temozolomide (TMZ) plus interferon (IFN)-β for glioblastoma. |