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Increased risk of knee osteoarthritis in patients using oral N-acetylcysteine: A nationwide cohort study

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Knee osteoarthritis (OA) is known to be a progressive degenerative disorder; however, recent evidence suggests that inflammatory mediators contribute to cartilage degradation. Studies have reported that Nacetylcysteine (NAC) had a promising effect on the reduction of the synthesis of proinflammatory and structural mediators by synovial cells. |

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