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Role of the Skp1 prolyl-hydroxylation/ glycosylation pathway in oxygen dependent submerged development of Dictyostelium
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Oxygen sensing is a near universal signaling modality that, in eukaryotes ranging from protists such as Dictyostelium and Toxoplasma to humans, involves a cytoplasmic prolyl 4-hydroxylase that utilizes oxygen and α-ketoglutarate as potentially rate-limiting substrates. |