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PDGFRα/β and VEGFR2 polymorphisms in colorectal cancer: Incidence and implications in clinical outcome

Angiogenesis plays an essential role in tumor growth and metastasis, and is a major target in cancer therapy. VEGFR and PDGFR are key players involved in this process. The purpose of this study was to assess the incidence of genetic variants in these receptors and its potential clinical implications in colorectal cancer (CRC). |