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Epidermal growth factor receptor gene polymorphisms are associated with prognostic features of breast cancer

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The epidermal growth factor receptor (EGFR) is differently expressed in breast cancer, and its presence may favor cancer progression. We hypothesized that two EGFR functional polymorphisms, a (CA)n repeat in intron 1, and a single nucleotide polymorphism, R497K, may affect EGFR expression and breast cancer clinical profile. |

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Báo cáo khoa học: Calmodulin-mediated regulation of the epidermal growth factor receptor