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Chemical constituents from methanolic extract of garcinia mackeaniana leaves and their antioxidant activity

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The phytochemical investigation of the methanolic extract of Garcinia mackeaniana Craib. leaves led to the isolation and determination of five known compounds, including one benzophenone 4,3',4'-trihydroxy-2,6-dimethoxybenzophenone (1), two flavone C-glucosides, vitexin and 2''-O-acetylvitexin, one biflavone, amentoflavone, and one phenolic compound, methyl protocatechuate. The chemical structures of compounds 1-5 were characterized by the NMR-spectral methods. All isolated compounds were separated from G. mackeaniana for the first time. Benzophenone derivative 1 has shown the IC50 value of 14.97 ± 0.8 µg/mL in the DPPH-antioxidantexamination. | Chemical constituents from methanolic extract of garcinia mackeaniana leaves and their antioxidant activity

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