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Estrogen receptor signaling regulates the expression of the breast tumor kinase in breast cancer cells

BRK is, a non-receptor tyrosine kinase, overexpressed in approximately 85% of human invasive ductal breast tumors. It is not clear whether BRK expression correlates with breast cancer subtypes, or the expression has prognostic or diagnostic significance. | Estrogen receptor signaling regulates the expression of the breast tumor kinase in breast cancer cells