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RNA-based analysis of ALK fusions in nonsmall cell lung cancer cases showing IHC/ FISH discordance

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Rearrangements of the anaplastic lymphoma kinase (ALK) belong to the promising targets in the therapy of advanced non-small cell lung cancer (NSCLC) and are predominantly detected by immunohistochemistry (IHC) and/or fluorescence in-situ hybridization (FISH). | RNA-based analysis of ALK fusions in nonsmall cell lung cancer cases showing IHC FISH discordance