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A web tool for designing and conducting phase I trials using the continual reassessment method

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Broad implementation of model-based dose-finding methods, such as the continual reassessment method (CRM), has been limited, with traditional or modified 3 + 3 designs remaining in frequent use. Part of the reason is the lack of reliable, easy-to-use, and robust software tools for designing and implementing more efficient designs. | A web tool for designing and conducting phase I trials using the continual reassessment method

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