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Is RNASEL:P.Glu265* a modifier of early-onset breast cancer risk for carriers of high-risk mutations

Breast cancer risk for BRCA1 and BRCA2 pathogenic mutation carriers is modified by risk factors that cluster in families, including genetic modifiers of risk. We considered genetic modifiers of risk for carriers of high-risk mutations in other breast cancer susceptibility genes. | Is RNASEL P.Glu265 a modifier of early-onset breast cancer risk for carriers of high-risk mutations