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Oct4 upregulates osteopontin via Egr1 and is associated with poor outcome in human lung cancer

Roles of cancer stem cells and early growth response gene 1 (Egr1) in carcinogenesis have been extensively studied in lung cancer. However, the role of Egr1 in the metastasis of lung cancer remains undetermined, especially in regard to stem cell-related pathways. | Oct4 upregulates osteopontin via Egr1 and is associated with poor outcome in human lung cancer