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Hypoxic induction of vasculogenic mimicry in hepatocellular carcinoma: Role of HIF-1 α, RhoA/ROCK and Rac1/PAK signaling

Vasculogenic mimicry (VM), defined as a capability of aggressive tumor Cells to mimic embryonic vasculogenic networks, caused poor prognosis in hepatocellular carcinoma (HCC). | Hypoxic induction of vasculogenic mimicry in hepatocellular carcinoma Role of HIF-1 α RhoA ROCK and Rac1 PAK signaling