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In vitro activity of a G-quadruplexstabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells

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Acute Myeloid Leukemia (AML) is a malignancy of myeloid precursor cells that arise from genomic alterations in the expression of key growth regulatory genes causing cells to assume an undifferentiated state and continue to proliferate. | In vitro activity of a G-quadruplexstabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells

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