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Evaluating the expression profile and stability of different UCOE containing vector combinations in mAb-producing CHO cells
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As the demand for monoclonal antibodies (mAb) increases, more efficient expression methods are required for their manufacturing process. Transcriptional gene silencing is a common phenomenon in recombinant cell lines which leads to expression reduction and instability. | Evaluating the expression profile and stability of different UCOE containing vector combinations in mAb-producing CHO cells