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Dynamic compression effects on immature nucleus pulposus: a study using a novel intelligent and me-chanically active bioreactor
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Previous cell culture and animal in vivo studies indicate the obvious effects of mechanical compression on disc cell biology. However, the effects of dynamic compression magnitude, frequency and duration on the immature nucleus pulposus (NP) from an organ-cultured disc are not well understood. | Dynamic compression effects on immature nucleus pulposus: a study using a novel intelligent and me-chanically active bioreactor