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Changing trends in resistance pattern of Methicillin resistant staphylococcus aureus in burn patients

Historically, S. aureus has been one of the most common pathogens which caused pyogenic local and systemic infections in both hospitals and community. Methicillin resistance in Staphylococcus aureus is associated with multidrug resistance, an aggressive course, increased mortality and morbidity in both community and health care facilities. This cross sectional study was carried out in a 70 burn patients from May 2016 to July 2018 at DR.S.C.G.M.C, Nanded India. Swabs were taken and cultured for bacterial isolation and identification following standard operative procedures. Antimicrobial susceptibility was performed by Kirby Bauer’s disc diffusion method which used a 30µg Cefoxitin disc according to CLSI 2018 guidelines. MRSA isolates showed high resistance to ciprofloxacin (76.4%), gentamicin (64.7%) as compared to other drugs. High prevalence of Ciprofloxacin resistance was detected. Multi resistant MRSA with a ‘D’ test positive was 79%. All MRSA isolates were sensitive to Vancomycin, Linezolid. MRSA had displayed increase in resistance to most antibiotics with ‘D’ test positive in recent years. Taking into consideration the prevalence of multidrug-resistance in MRSA, resistance patterns should be evaluated periodically and antibiotic therapy should be guided by susceptibility testing. | Changing trends in resistance pattern of Methicillin resistant staphylococcus aureus in burn patients