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Influence of angiogenic mediators and bone remodelling in Paget´s disease of bone
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Paget´s disease of bone (PDB) is characterized by increased bone resorption followed by an excessive compensatory bone formation, with an abnormal bone structure with altered mechanical properties. Pagetic bone also has a higher vascularization and marrow fibrosis. | Influence of angiogenic mediators and bone remodelling in Paget´s disease of bone